An integrated, mathematically and computationally sophisticated introduction to physics and chemistry, drawing on examples from biological systems. This year long, four course sequence is a multidisciplinary course taught across multiple departments with the following faculty: T. Gregor, J. Shaevitz (PHY); O. Troyanskaya (COS); J. Akey (EEB); E. Wieschaus, M. Wuhr (MOL); B. Bratton, J. Gadd, A. Mayer, Q. Wang (LSI). Five hours of lecture, one experimental lab, one three-hour precept.

An integrated, mathematically and computationally sophisticated introduction to physics and chemistry, drawing on examples from biological systems. This year long, four course sequence is a multi-disciplinary course taught across multiple departments with the following faculty: T. Gregor, J. Shaevitz (PHY); O. Troyanskaya (COS); J. Akey (EEB); E. Wieschaus, M. Wuhr (MOL); B. Bratton, J. Gadd, A. Mayer, Q. Wang (LSI). Five hours of lecture, one three-hour lab, one three-hour precept.

The completion of the human genome and the continuing effort to sequence tens of thousands of human genomes is yielding unprecedented insights into human biology and the evolutionary history of our species. We will review the key advances enabling researchers to decipher the structure and function of the human genome as well as the genetic basis of variation among individuals and populations. Topics include the evolutionary origins and current structure of human populations, methods for detecting genomic features, cancer genomics and mapping the genes and variants underlying population-specific adaptations and disease susceptibility.