Biosensing and Diagnostics

An introductory multidisciplinary course for undergraduate and first-year graduate engineering students, covering fundamental principles, applications, and new advances in biosensing and diagnostics. Topics include biomarkers (small molecules, proteins, nucleic-acids, and cells), detection methods (electrochemical assay, colorimetric assay, immunoassay, nucleic acid hybridization assay, PCR, pure physical detection), signal generation, assay enhancement, assay characterization/validation, molecular binding theory, small molecule detection (hapten), competitive assays, self-flow assays, diagnostics, FDA 510(k), microfluidics, microarrays, etc.