Biomolecular Engineering

This course will focus on the structure, function, design and engineering of biomacromolecules. After a brief review of protein and nucleic acid chemistry and structure, we will delve into rational, evolutionary, and computational methods for the design of these molecules. Specific topics to be covered include protein and RNA-based switches and sensors, unnatural amino acids and nucleotides, enzyme engineering, integration of these parts via synthetic biology, and applications in biotechnology industries.