Modern Biophysics and Systems Biology

At a 10 nanometer scale, protein machines 'walk' on microtubule tracks. At a scale 10,000 times larger, networks of interacting genes pattern a developing embryo into different body regions. This course will examine these and other complex biological systems at the molecular, cellular, and multicellular scales. In parallel, we will cover emerging methods for quantitatively probing and analyzing biological systems. Specific topics will include structural biology from crystallography to cryo-electron microscopy, enzyme kinetics, gene regulatory networks, next-generation sequencing, data mining, simulating biological models and image analysis.